Detail infomation of NONHSAG012810.2--NONCODE

An integrated knowledge database dedicated to ncRNAs, especially lncRNAs.

Detail infomation of NONHSAG012810.2

General info

NONCODE GENE ID	NONHSAG012810.2
Chromosome	chr12
Start Site	132593030
End Site	132596086
Strand	-
Length	1117
Assembly	hg38
Class	Linc;
Other Gene Versions	NONHSAG012810.1(old version)

Transcripts in Gene

NONCODE TRANSCRIPT ID

NONHSAT164319.1

NONHSAT032096.2

NONHSAT032097.2

NONHSAT032098.2

Expression Profile (Data Source:Human Body Map)

adipose	adrenal	brain	brain_R	breast	colon
0.675835	1.15063	0.312601	0.264631	0.530234	0.131594
foreskin	heart	heart_R	HLF_1	HLF_2	kidney
0.182814	0.107768	0.1149	0.0583444	0.725734	0.257774
liver	liver_R	lung	lymphNode	ovary	placenta_R
0.287672	0	0.516081	0.555329	0.285258	0.469421
prostate	skeltalMuscle	testes	testes_R	thyroid	whiteBloodCell
0.314203	0.268335	4.82898	7.0178	0.26357	0.0145362

Expression profile of NONHSAG012810 in Human tissues

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Exosome Expression Profile (Data Source: NCBI GEO)

A431_cellLine (Squamous Cell Carcinoma Cell Line Exosomes)	BJ_cellLine (Foreskin Fibroblast Cell Line Exosomes)	HepG2_cellLine (Hepatocellular Carcinoma Cell Line Exosomes)	HUVEC_cellLine (Human Umbilical Vein Endothelial Cell Line Exosomes)	invasive_NFPAs (Invasive Non-functional Pituitary Adenomas Exosomes)
0	0.433881	2.91614	0.379952	8.50486
non-invasive_NFPAs (Non-invasive Non-functional Pituitary Adenomas Exosomes)	MCF7_cellLine (Human Breast Cancer Cell Line Exosomes)	MDA-MB-231_cellLine (Human Breast Cancer Cell Line Exosomes)	tuberculosis_patients_serum (Active Tuberculosis Patients Serum Exosomes)	normal_people_blood (Normal People Blood Exosomes)
11.5125	0	0	11.6307	0

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Conservation Info

Chordata
- Vertebrates
  - Manmals
    - Primates
      - Human
      - Chimp : chr12( len:3101 )
      - Gorilla : chr12( len:3235 )^T
      - Orangutan : chr12( len:3105 )
      - Rhesus : N/A
    - Rodents
      - Mouse : N/A
      - Rat : N/A
    - Laurasiatheria
      - Pig : N/A
      - Cow : N/A
    - Opossum : N/A
    - Platypus : N/A
  - Birds
    - Chicken : N/A
- Actinopteryqii
  - Zebrafish : N/A

Note: T = There are transcripts in this region.

Disease related

Disease:

NONCODE ID

Gene Symbol

Disease name

Source Database

Source PMID

Mutations:

NONCODE ID	SNP ID	GWAS trait	Source PMID
NONHSAG012810.2	rs1882298	Gene expression of POLE (probeID ILMN_1728199) in cerebellum in Alzheimer's disease cases and controls	22685416
NONHSAG012810.2	rs1882298	Gene expression of POLE (probeID ILMN_1728199) in temporal cortex in Alzheimer's disease cases and controls	22685416

Potential Function

GO Number	Description
GO:0007409	axonogenesis
GO:0007155	cell adhesion
GO:0006366	transcription from RNA polymerase II promoter
GO:0007286	spermatid development
GO:0042997	negative regulation of Golgi to plasma membrane protein transport
GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0016485	protein processing
GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0030048	actin filament-based movement
GO:0007281	germ cell development

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